Mark Ealham took three wickets after tea to reduce Yorkshire to 107-4 as Notts took control on day three at Trent Bridge.
Second innings fifties from Bilal Shafayat, Mark Wagh, Samit Patel and Graeme Swann helped Notts to 350 all out as Yorkshire began their second innings 402 runs behind.
Joe Sayers was caught behind off Charlie Shreck for 2 before Ealham registered 3-23 to reduce Yorkshire to 75-4 from 75-1.
“There wasn’t much happening for us at 75-1 but Mark produced a great spell and he’s given us every chance of winning the game,” said Notts Director of Cricket Mick Newell.
“I would have liked to have seen a century from one of the batsmen but there were some good scores and we have enough time to take the wickets.
“We need to keep focussed and we know that it could take time but be want to get into the tail and finish the job.”
Yorkshire bowler Rana Naved left the field midway through an over with a stiff neck having dismissed Mark Wagh, Samit Patel and Matt Wood.
Patel and Adam Voges enjoyed a 78 run partnership and after Voges went leg-before to Bresnan, Graeme Swann hit six fours and a six on his way to 57.
Notts fell from 336-7 to 350 all out after Swann was stumped by Bresnan but his contribution kept the home side firmly in command.
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